And lastly, clonidine enhances neuraxial opioids and, in combination with fentanyl, interacts in an additive method, which can decrease the dose of each component by 60% for postoperative analgesia. For people who get dizzy when standing: This condition is referred to as orthostatic hypotension. Clonidine may make this affliction https://www.proleviate.com/post/the-new-pain-killer-conolidine