This mechanism is probably with the induction of hepatic microsomal enzymes that metabolize the antibiotic. If phenobarbital and doxycycline are administered concurrently, the medical response to doxycycline need to be monitored closely. Phenytoin, sodium valproate, valproic acid: The influence of barbiturates about the metabolism of phenytoin seems to get variable. https://mylesyxadw.actoblog.com/29346830/new-step-by-step-map-for-nembutal